Megan Mullally has returned to her iconic role as Karen Walker on NBC's "Will & Grace," which begins its final season October 24.

The role has garnered her two Emmy Awards and six additional nominations, with the series earning a total of 18 Emmys and 91 nominations to date. The series remains one of the few in television history where each member of the "Will & Grace" cast has won an Emmy. She has also earned four Screen Actors Guild Awards and received four Golden Globe nominations for her work on "Will & Grace."

Mullally starred alongside Rob Lowe and Jenna Fischer in Sky TV's "You, Me and the Apocalypse," which aired on NBC in 2015 following a run in the U.K. She also co-starred on Rob Corddry's satirical Emmy-winning TV series "Childrens Hospital" and recurred on "Parks and Recreation" as the evil Tammy, opposite her real-life husband, Nick Offerman. 

Mullally and Offerman also guest-starred in an episode of CBS's "Life in Pieces." She had a recurring role on Fox's animated hit "Bob's Burgers," appeared on the acclaimed series "Party Down," and guested on the Emmy-winning "30 Rock," as well as "Web Therapy," "Trophy Wife," "Up All Night" and "Happy Endings." Other credits include "The Ellen Burstyn Show," "Seinfeld," "Frasier," "Wings," "Mad About You," "Caroline in the City," "China Beach," "Murder, She Wrote," "My Life and Times" and "Rachel Gunn, R.N."

On the stage, Mullally has appeared in two Broadway musicals: a 1994 revival of "Grease," with Rosie O'Donnell, and 1995's "How to Succeed in Business Without Really Trying," opposite Matthew Broderick. She returned to Broadway in the Mel Brooks original musical "Young Frankenstein." She also starred in the New Group's production of Sharr White's "Annapurna," opposite Offerman. This followed a successful 2009 run at L.A.'s Odyssey Theatre in Adam Bock's "The Receptionist," for which she was awarded a Backstage West Garland Award. 

Mullally returned to Broadway in 2014 for Terence McNally's "It's Only a Play," alongside Nathan Lane, Matthew Broderick, F. Murray Abraham, Stockard Channing, Rupert Grint and Micah Stock. That same year she co-starred in a critically applauded performance opposite Lane in "Guys and Dolls" at Carnegie Hall.

For her film projects, Mullally co-starred with James Franco and Bryan Cranston in John Hamburg's "Why Him?" and also appeared in James Franco's critically acclaimed "The Disaster Artist," as well as the Bob Byington-directed comedy "Infinity Baby," alongside Offerman. Other movie credits include "Where'd You Go, Bernadette," "Alexander and the Terrible, Horrible, No Good, Very Bad Day," "Smashed," "The Kings of Summer," "Ernest & Celestine," "Date and Switch," "Somebody Up There Likes Me" and "G.B.F." She also voiced a character in "Hotel Transylvania 2."

Mullally and Offerman toured their comedy show, "Summer of 69: No Apostrophe," which was recorded for a comedy special in 2017.